For a general user the first three are usually more than sufficient to make your Vista faster. The remaining are some more which a tweak enthusiast may wish to consider. Utilities like WinPatrol or Tune-Up Utilities can help you in most of the cases.
1. Restrict the no. of start-ups. Why have programs starting up when you dont really use them. Even those you use can always be started manually by clicking on the. I personally prefer not to have ANY starups. I click on my Internet Defense Suite manually, before connecting to the Internet. So decide for yourself which one's you really need as start-ups.
2. Disable services which one may not require. For example, if your pc is a stand-alone one, there may be sevral services which you can disable or switch over to manual mode. Auto-starting and closing down of services takes time & resources. These can be saved. BlackViper's Vista Service Configurations is an excellent guide to follow.
3. Reducing visual effects (eye candy).
Right-click on